This 5-ingredient pesto chicken breast is the ultimate weeknight dinner solution — quick to prepare, bursting with flavor, and incredibly satisfying. It combines tender, juicy chicken breasts with the vibrant, herbaceous kick of basil pesto and a blanket of melty mozzarella. With minimal prep and a cook time under 30 minutes, this recipe delivers gourmet taste with pantry simplicity. Perfect for busy schedules, it’s a low-effort, high-reward meal that pairs beautifully with pasta, salad, or roasted vegetables.

FULL RECIPE

Ingredients

• 2 boneless, skinless chicken breasts
• ½ teaspoon salt
• ¼ teaspoon black pepper
• ½ cup basil pesto (store-bought or homemade)
• 1 cup shredded mozzarella cheese

Directions

1. Preheat your oven to 400°F (200°C). Lightly grease a baking dish or line it with parchment paper.
2. Season both sides of the chicken breasts with salt and pepper. Place them in the prepared baking dish.
3. Spoon basil pesto evenly over each chicken breast, spreading it out to cover the surface.
4. Sprinkle the shredded mozzarella cheese generously over the top of the pesto-coated chicken.
5. Bake uncovered for 20–25 minutes, or until the chicken is fully cooked (internal temperature should reach 165°F or 74°C) and the cheese is melted and slightly golden.
6. Remove from the oven and let rest for 5 minutes before serving.
7. Garnish with fresh basil if desired and serve with your favorite sides.

Nutrition Facts 

• Calories: 420
• Total Fat: 28g
• Saturated Fat: 8g
• Cholesterol: 100mg
• Sodium: 720mg
• Total Carbohydrates: 4g
• Dietary Fiber: 0g
• Sugars: 1g
• Protein: 38g
• Vitamin A: 15% DV
• Calcium: 20% DV
• Iron: 6% DV
• Potassium: 500mg

Health Benefits of Pesto Chicken

While indulgent in flavor, pesto chicken can be a relatively healthy main dish when prepared thoughtfully. Chicken breast is a lean protein source that supports muscle health and satiety without excess fat. Pesto, often made with olive oil, basil, garlic, and nuts, provides heart-healthy monounsaturated fats and antioxidants. Mozzarella adds calcium and protein, especially if using part-skim varieties. The recipe is naturally low in carbs, making it compatible with keto, low-carb, and gluten-free diets. Pairing it with vegetables or salad increases fiber and micronutrient intake for a more complete meal.

Choosing the Right Chicken

The success of this dish hinges on using quality chicken breasts. Opt for boneless, skinless cuts that are similar in thickness to ensure even cooking. If the breasts are particularly thick, slicing them in half horizontally or pounding them to uniform thickness can prevent dryness. Organic or free-range chicken is ideal for those concerned about additives or ethical sourcing. Proper seasoning of the meat before baking helps enhance flavor, especially when working with lean cuts that can easily become bland if not well prepared.

The Role of Basil Pesto

Pesto is the star ingredient that defines this dish. Its blend of fresh basil, Parmesan cheese, garlic, olive oil, and pine nuts creates a sauce that’s vibrant, aromatic, and slightly nutty. It serves as both a seasoning and a moisture-retaining barrier during baking. While store-bought pesto is convenient and widely available, homemade versions allow for greater control over freshness, texture, and salt content. For variety, sun-dried tomato pesto or arugula walnut pesto can be used as substitutes to bring in new flavor profiles without sacrificing the core appeal of the recipe.

Cheese Options and Substitutions

Mozzarella is a natural choice for topping pesto chicken due to its mild flavor and excellent melting qualities. Shredded mozzarella creates a bubbly, golden layer that locks in moisture and contrasts with the pesto’s texture. However, other cheeses can be substituted depending on personal preference or what’s available. Try provolone for a stronger taste, fontina for smooth meltability, or even a sprinkle of crumbled feta for tang. Those avoiding dairy may opt for plant-based cheese alternatives, though the melt and flavor may vary slightly from traditional versions.

Serving Suggestions

Pesto chicken breast pairs beautifully with a range of side dishes, allowing you to adapt it to different cuisines or dietary needs. For a wholesome plate, serve it alongside roasted vegetables, sautéed greens, or a simple arugula salad dressed with lemon. Pasta tossed in olive oil or a light cream sauce makes a satisfying pairing, as does a bed of quinoa or cauliflower rice for low-carb options. For a comfort-food twist, consider serving the chicken over garlic mashed potatoes or tucked into a warm ciabatta roll as a sandwich.

Ideal Drink Pairings

The bright, herbaceous notes of pesto call for drink pairings that can either complement or contrast the dish’s flavor. A crisp white wine like Sauvignon Blanc or Pinot Grigio pairs well with the basil and garlic elements, offering refreshing acidity. For red wine lovers, a light-bodied Pinot Noir can balance the cheese and meat without overwhelming the palate. Beer drinkers may enjoy pairing this dish with a hoppy IPA or a pale ale that enhances the pesto’s punch. For non-alcoholic options, sparkling water with lemon or a cold herbal iced tea works wonderfully.

Make-Ahead and Meal Prep Tips

This recipe is highly meal-prep friendly and can be made ahead in several ways. Season and marinate the chicken in pesto the night before to enhance the flavor, then bake when ready. Cooked pesto chicken also stores well and can be reheated without losing too much moisture, making it great for lunchboxes or quick dinners. Slice leftover chicken to use in wraps, salads, or grain bowls throughout the week. For added convenience, double the recipe and freeze one batch (uncooked) with pesto already applied, so it’s ready to go straight into the oven later.

Storage and Reheating Advice

Store leftover pesto chicken in an airtight container in the refrigerator for up to 3 to 4 days. To maintain its juiciness, reheat gently in the oven at 300°F (150°C) covered with foil, or microwave in short intervals with a splash of water to prevent drying out. Avoid overheating as the cheese may become rubbery. This dish can also be frozen, preferably before baking. If freezing after cooking, let the chicken cool completely, then wrap tightly and store for up to 2 months. Thaw in the fridge overnight before reheating.

Common Mistakes to Avoid

One frequent error is overbaking the chicken, which results in dryness. Always check for doneness using a meat thermometer to ensure the internal temperature reaches 165°F (74°C) and no higher. Another mistake is applying too much pesto, which can lead to excess oil pooling in the baking dish. A thin, even coating is usually sufficient. Also, don’t skip the seasoning step — while pesto is flavorful, it benefits from a little added salt and pepper on the chicken for depth. Finally, resist the urge to use cold chicken straight from the fridge; allowing it to rest at room temperature for 15 minutes ensures more even cooking.

Conclusion

This 5-ingredient pesto chicken breast recipe offers a masterclass in simplicity and flavor. It’s proof that with just a handful of quality ingredients, you can create a delicious, versatile, and healthy meal in under 30 minutes. From weeknight dinners to meal prep staples, this dish adapts beautifully to various lifestyles and preferences. With its rich flavor, ease of preparation, and wide appeal, pesto chicken is sure to become a regular feature in your kitchen — a go-to option that never fails to satisfy.